X-ray computed tomography (XCT) is a powerful volumetric non-destructive testing tool. In this contribution, its application for large pieces of equipment is demonstrated, after the main components of an XCT scanner are described. While the technology has been well known in the scientific community for many years, its industrial-scale use is relatively new, especially as far as very large units are concerned. In a number of case studies, the benefits to the failure analyst of readily available XCT machines will be shown. The advantages in employing non-destructive XCT for metallurgical root cause failure analysis, prior to cutting up a failed part for sectioning and opening of cracks or other imperfections will be revealed. It will be indicated how XCT can be conveniently applied in failure cases, for the sake of both the failure analyst and the fractographer. XCT can be used as a first testing method to get an understanding of the exact location of imperfections, field of porosity, crack systems and the like, before macro- and microstructural anomalies are opened by the fractographer. To state it more clearly, the fractographer who has a high-powered XCT, with excellent spacial resolution at his or her disposal, will never again run the risk of cutting away a crack tip that is so valuable in determining the fracture mode.